The antipsychotic aripiprazole induces peripheral antinociceptive effects through PI3Kγ/NO/cGMP/KATP pathway activation

Bckground Aripiprazole is an antipsychotic drug used to treat schizophrenia and bipolar disorder. Recently, its peripheral analgesic component was evaluated, however, the mechanism involved in this effect is not fully established. Therefore, the aim of the study was to obtain pharmacological evidenc...

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Veröffentlicht in:	European journal of pain 2022-04, Vol.26 (4), p.825-834
Hauptverfasser:	Ferreira, Renata C. M., Almeida, Douglas L., Duarte, Igor D. G., Aguiar, Daniele C., Moreira, Fabrício A., Romero, Thiago R. L.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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