Recent Investigations on Neurotransmitters’ Role in Acute White Matter Injury of Perinatal Glia and Pharmacotherapies—Glia Dynamics in Stem Cell Therapy

Periventricular leukomalacia (PVL) and cerebral palsy are two neurological disease conditions developed from the premyelinated white matter ischemic injury (WMI). The significant pathophysiology of these diseases is accompanied by the cognitive deficits due to the loss of function of glial cells and...

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Veröffentlicht in:	Molecular neurobiology 2022-04, Vol.59 (4), p.2009-2026
Hauptverfasser:	Beeraka, Narasimha M., Vikram, P. R. Hemanth, Greeshma, M. V., Uthaiah, Chinnappa A., Huria, Tahani, Liu, Junqi, Kumar, Pramod, Nikolenko, Vladimir N., Bulygin, Kirill V., Sinelnikov, Mikhail Y., Sukocheva, Olga, Fan, Ruitai
Format:	Artikel
Sprache:	eng
Schlagworte:	Axons Biomedical and Life Sciences Biomedicine Blood vessels Brain Injuries - complications Calcium influx Cell Biology Cell therapy Cell- and Tissue-Based Therapy Cerebral Palsy Cognitive ability Corpus callosum Depolarization Drug therapy Excitotoxicity Glial cells Glutamate receptors Glutamic Acid Glutamic acid receptors (ionotropic) Humans Infant Infant, Newborn Ischemia Leukomalacia, Periventricular Membrane potential Molecular modelling N-Methyl-D-aspartic acid receptors Nerves Neurobiology Neuroglia - metabolism Neurological diseases Neurology Neuronal-glial interactions Neuroplasticity Neurosciences Neurotransmitter Agents Neurotransmitters Paralysis Pathophysiology Periventricular leukomalacia Receptors, Glutamate - metabolism Receptors, N-Methyl-D-Aspartate - metabolism Stem cells Substantia alba White Matter - metabolism
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