Simultaneous determination of moxifloxacin with NSAIDs in API, dosage and serum by reverse phase high-performance liquid chromatography: Application to in vitro drug interactions

Experimental design is a significant tool for optimization and validation for the development of HPLC methods to determine API in both human serum and pharmaceutical formulations. In this study, RP-HPLC method is developed and validated for the simultaneous determination of moxifloxacin and NSAIDs....

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Veröffentlicht in:	Pakistan journal of pharmaceutical sciences 2021-11, Vol.34 (6), p.2091-2099
Hauptverfasser:	Akhtar, Mahwish, Gul, Somia, Shamim, Sana, Siddiqui, Rubina
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - blood Anti-Inflammatory Agents, Non-Steroidal - blood Chemical properties Chromatography, High Pressure Liquid Chromatography, Reverse-Phase Complications and side effects Dosage and administration Drug Combinations Drug Interactions High performance liquid chromatography Humans Limit of Detection Moxifloxacin Moxifloxacin - blood Nonsteroidal anti-inflammatory drugs Pharmaceutical research Reproducibility of Results Tablets
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