DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

DNA nanotechnology enables programmable self-assembly of nucleic acids into user-prescribed shapes and dynamics for diverse applications. This work demonstrates that concepts from DNA nanotechnology can be used to program the enzymatic activity of the phage-derived T7 RNA polymerase (RNAP) and build...

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Veröffentlicht in:	Journal of Visualized Experiments 2021-12 (178)
Hauptverfasser:	Lee, Ryan C., Douglas, Travis R., Chou, Leo Y. T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioengineering Computers, Molecular DNA - genetics DNA-Directed RNA Polymerases - genetics DNA-Directed RNA Polymerases - metabolism Promoter Regions, Genetic RNA - metabolism Transcription, Genetic
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