Apoptotic protease activating factor-1 gene and MicroRNA-484: A possible interplay in relapsing remitting multiple sclerosis

•Bioinformatics analysis revealed miR-484 involvement in the regulation of apoptotic protease activating factor-1 (APAF-1) gene expression.•APAF-1 mRNA is downregulated and miR-484 is overexpressed in the peripheral blood mononuclear cells (PBMCs) of RRMS patients.•miR-484 might be implicated in RRM...

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Veröffentlicht in:	Multiple sclerosis and related disorders 2022-02, Vol.58, p.103502-103502, Article 103502
Hauptverfasser:	Mohamed, Dalia Abdel Wahab, Selim, Heba M., Elmazny, Alaa, Genena, Ali, Nabil, Mai Mohamed
Format:	Artikel
Sprache:	eng
Schlagworte:	APAF-1 Apoptotic Protease-Activating Factor 1 Biomarkers Humans Leukocytes, Mononuclear MicroRNAs - genetics miR-484 Multiple sclerosis Multiple Sclerosis - genetics Multiple Sclerosis, Relapsing-Remitting - diagnosis Peptide Hydrolases
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