Internalization Mechanism of Phenylboronic-Acid-Decorated Nanoplatform for Enhanced Nasal Insulin Delivery

Insulin injection causes great pain to the patient, and nasal mucosal administration of insulin is a novel route for the treatment of diabetes. This strategy could protect insulin from either extensive first-pass metabolism or enzyme degradation in the gastrointestinal tract. With the dynamic borona...

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Veröffentlicht in:ACS applied bio materials 2020-04, Vol.3 (4), p.2132-2139
Hauptverfasser: Wei, Xiaosong, Duan, Xiaozhuang, Zhang, Yufei, Ma, Zhuang, Li, Chaoxing, Zhang, Xinge
Format: Artikel
Sprache:eng
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