Microdialysis techniques and microdialysis-based patient-near diagnostics

Microdialysis techniques and microdialysis-based patient-near diagnostics

This article will debate the usefulness of POCT measurements and the contribution microdialysis can make to generating valuable information. A particular theme will be the rarely considered difference between ex vivo sampling, which typically generates only a static measure of concentration, and in...

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Veröffentlicht in:Analytical and bioanalytical chemistry 2022-04, Vol.414 (10), p.3165-3175
Hauptverfasser: O’Connell, Mark Thomas, Krejci, Jan
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Analytical Chemistry
Biochemistry
Biosensors
Catheters
Characterization and Evaluation of Materials
Chemistry
Chemistry and Materials Science
Dialysis
Food Science
Glucose monitoring
Humans
Laboratory Medicine
Mass transfer
Medical tests
Methods
Microdialysis
Microdialysis - methods
Monitoring/Environmental Analysis
Patients
Point of care testing
Regulatory approval
Review
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Beschreibung
Zusammenfassung:This article will debate the usefulness of POCT measurements and the contribution microdialysis can make to generating valuable information. A particular theme will be the rarely considered difference between ex vivo sampling, which typically generates only a static measure of concentration, and in vivo measurements that are subject to dynamic changes due to mass transfer. Those dynamic changes provide information about the patients’ physiological state.
ISSN:1618-2642
1618-2650
DOI:10.1007/s00216-021-03830-6