A novel strategy by integrating chemical profiling, molecular networking, chemical isolation, and activity evaluation to target isolation of potential anti-ACE2 candidates in Forsythiae Fructus

Traditional Chinese medicine (TCM) is regarded as a large database containing hundreds to thousands of chemical constituents that can be further developed as clinical drugs, such as artemisinin in Artemisia annua. However, effectively exploring novel candidates is still a challenge faced by research...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2022-02, Vol.96, p.153888-153888, Article 153888
Hauptverfasser:	Li, Chang, Sun, Chen-Zhi, Yang, Yi-Hui, Ma, Nan, Wang, Ya-Jing, Zhang, Feng-Xiang, Pei, Yue-Hu
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme 2 Anti-ACE2 activity Chemical profiling Chromatography, High Pressure Liquid COVID-19 Drugs, Chinese Herbal Forsythiae fructus Humans Molecular networking Plant Extracts SARS-CoV-2 Tandem Mass Spectrometry
Online-Zugang:	Volltext
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