Controlling chirality in the synthesis of 4 + 4 diastereomeric amine macrocycles derived from trans -1,2-diaminocyclopentane and 2,6-diformylpyridine

A few suitably long dialdehyde and primary diamine building blocks of a predetermined chirality have been designed and synthesized to enable controlled and efficient synthesis of all six possible diastereomers of 4 + 4 macrocyclic amine derived from -1,2-diaminocyclopentane (DACP) and 2,6-diformypyr...

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Veröffentlicht in:	Organic & biomolecular chemistry 2022-02, Vol.20 (5), p.1080-1094
Hauptverfasser:	Fedorowicz, Dominika, Banach, Sylwia, Koza, Patrycja, Frydrych, Rafał, Ślepokura, Katarzyna, Gregoliński, Janusz
Format:	Artikel
Sprache:	eng
Schlagworte:	Chirality Circular dichroism Configurations Diamines Diastereoisomers Dichroism Enantiomers NMR Nuclear magnetic resonance Optical activity Single crystals Synthesis Tartaric acid
Online-Zugang:	Volltext
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