Myostatin increases human trophoblast cell invasion by upregulating N-cadherin via SMAD2/3-SMAD4 signaling

Placental insufficiency disorders are major obstetric complications that share a common phenomenon of poor placental trophoblast cell invasion and remodeling of uterine tissues. Myostatin is a transforming growth factor (TGF)-β superfamily member well known for its important role in muscle growth co...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biology of reproduction 2022-06, Vol.106 (6), p.1267-1277
Hauptverfasser:	AbdelHafez, Faten, Klausen, Christian, Zhu, Hua, Leung, Peter C.K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cadherins Cytokeratin Gene expression Growth factors Gynecology invasion IUGR Kinases Myostatin N-Cadherin Obstetrics Placenta placental insufficiency Preeclampsia Pregnancy Proteins RESEARCH ARTICLE Research centers Reverse transcription siRNA Smad2 protein Smad4 protein Uterus
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!