Self-Assembled Plasmid Delivery System for PPM1D Knockout to Reverse Tumor Malignancy

Gene delivery vectors possess critical roles in effective genome editing. In this study, a multiple functional vector for encapsulating CRISPR/Cas9 plasmid was designed to knock out PPM1D gene and prevent cancer malignancy. The plasmid was complexed with a KALA peptide with the capability of endosom...

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Veröffentlicht in:	ACS applied bio materials 2020-11, Vol.3 (11), p.7831-7839
Hauptverfasser:	Ren, Xiao-He, He, Xiao-Yan, Liu, Bo-Ya, Xu, Chang, Cheng, Si-Xue
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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