Binding Sites of a Positron Emission Tomography Imaging Agent in Alzheimer’s β‑Amyloid Fibrils Studied Using 19F Solid-State NMR

Amyloid imaging by positron emission tomography (PET) is an important method for diagnosing neurodegenerative disorders such as Alzheimer’s disease. Many 11C- and 18F-labeled PET tracers show varying binding capacities, specificities, and affinities for their target proteins. The structural basis of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of the American Chemical Society 2022-01, Vol.144 (3), p.1416-1430
Hauptverfasser: Duan, Pu, Chen, Kelly J, Wijegunawardena, Gayani, Dregni, Aurelio J, Wang, Harrison K, Wu, Haifan, Hong, Mei
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!