Binding Sites of a Positron Emission Tomography Imaging Agent in Alzheimer’s β‑Amyloid Fibrils Studied Using 19F Solid-State NMR
Amyloid imaging by positron emission tomography (PET) is an important method for diagnosing neurodegenerative disorders such as Alzheimer’s disease. Many 11C- and 18F-labeled PET tracers show varying binding capacities, specificities, and affinities for their target proteins. The structural basis of...
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Veröffentlicht in: | Journal of the American Chemical Society 2022-01, Vol.144 (3), p.1416-1430 |
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Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
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