Structural brain and spinal cord damage in symptomatic and pre-symptomatic VAPB-related ALS

The VAPB gene is associated with fALS (fALS 8). This disease presents a variable phenotype and no study sought to characterize its neuroanatomical abnormalities until now. This study aims to evaluate structural brain and spinal cord abnormalities in symptomatic and pre-symptomatic VAPB-related ALS....

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Veröffentlicht in:	Journal of the neurological sciences 2022-03, Vol.434, p.120126-120126, Article 120126
Hauptverfasser:	Leoni, Tauana B., Rezende, Thiago Junqueira R., Peluzzo, Thiago M., Martins, Melina P., Neto, Antonio Rodrigues Coimbra, Gonzalez-Salazar, Carelis, Cruzeiro, Marcelo Maroco, Camargos, Sarah Teixeira, de Souza, Leonardo Cruz, França, Marcondes C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - diagnostic imaging Amyotrophic Lateral Sclerosis - genetics Atrophy Brain - diagnostic imaging Genetics Humans Magnetic Resonance Imaging MRI Presymptomatic Spinal Cord - diagnostic imaging VAPB Vesicular Transport Proteins White Matter - diagnostic imaging
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