Additive cell protective and oxidative stress reducing effects of combined treatment with cromolyn sodium and masitinib on MPTP-induced toxicity in SH-SY5Y neuroblastoma cells

The suppression of oxidative-stress induced neurotoxicity by antioxidants serves as a potential preventive strategy for neurodegenerative diseases. In this study, we aimed to investigate the cell protective and antioxidant effects of masitinib and cromolyn sodium against toxin-induced neurodegenerat...

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Veröffentlicht in:	Chemico-biological interactions 2022-02, Vol.354, p.109808, Article 109808
Hauptverfasser:	Goksu Erol, Azize Yasemin, Kocanci, Fatma Gonca, Demir-Dora, Devrim, Uysal, Hilmi
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Methyl-4-phenylpyridinium - toxicity Antioxidants - pharmacology Apoptosis - drug effects Benzamides - pharmacology Cell Line, Tumor Cell Survival - drug effects Cromolyn sodium Cromolyn Sodium - pharmacology Humans Masitinib Neuroblastoma - drug therapy Neuroblastoma - metabolism Neuroblastoma - pathology Neurodegeneration Neuroprotective Agents - pharmacology Nitric Oxide - metabolism Oxidative stress Oxidative Stress - drug effects Piperidines - pharmacology Pyridines - pharmacology SH-SY5Y Cells Thiazoles - pharmacology Transforming Growth Factor beta1 - metabolism Transforming growth Factor-β1
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