miR-1 Regulates Differentiation and Proliferation of Goat Hair Follicle Stem Cells by Targeting IGF1R and LEF1 Genes

Hair follicle stem cells (HFSCs) play a significant role in hair development. miR-1 has been reported as an important regulatory factor that affects hair follicle growth and development, but its regulatory mechanism on HFSC development remains unknown. In this study, the molecular mechanism of miR-1...

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Veröffentlicht in:	DNA and cell biology 2022-02, Vol.41 (2), p.190-201
Hauptverfasser:	Yan, Hailong, Jin, Miaohan, Li, Yan, Gao, Ye, Ding, Qiang, Wang, Xiaolong, Zeng, Wenxian, Chen, Yulin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - genetics Cell proliferation Cell Proliferation - genetics Cells, Cultured Differentiation Genes Goats - genetics Hair Hair Follicle - cytology Hair Follicle - growth & development Hair Follicle - metabolism Lymphoid Enhancer-Binding Factor 1 - genetics Lymphoid Enhancer-Binding Factor 1 - metabolism MicroRNAs - genetics MicroRNAs - metabolism miRNA Molecular modelling Receptor, IGF Type 1 - genetics Receptor, IGF Type 1 - metabolism Regulatory mechanisms (biology) Stem cells Stem Cells - cytology Stem Cells - metabolism
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