Immune profile by multiplexed immunohistochemistry associated with recurrence after chemoradiation in rectal cancer

Background and Aim Evidence has emerged that a pretreatment immune profile in rectal cancer is associated with response to chemoradiotherapy (CRT) and recurrence after CRT. However, few studies have evaluated the immune profile differences after CRT regarding recurrence and nonrecurrence. Methods We...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2022-03, Vol.37 (3), p.542-550
Hauptverfasser:	Hong, Seung Wook, Lee, Seohyun, Kim, Yun Jae, Ahn, Soyeon, Park, In Ja, Hong, Seung‐Mo, Hwang, Sung Wook, Park, Sang Hyoung, Yang, Dong‐Hoon, Ye, Byong Duk, Byeon, Jeong‐Sik, Yang, Suk‐Kyun, Kim, Jaeil, Kim, Sang‐Yeob, Myung, Seung‐Jae
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer CD3 antigen CD8 antigen Chemoradiotherapy Colorectal cancer Female Foxp3 protein Humans Immunohistochemistry Lymphocytes T Lymphocytes, tumor Male Neoplasm Recurrence, Local Patients PD-L1 protein Rectal neoplasms Rectal Neoplasms - metabolism Rectal Neoplasms - pathology Rectal Neoplasms - therapy Rectum Stromal cells Treatment Outcome Tumors
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