The regulation of Msx1 by BMP4/pSmad1/5 signaling is mediated by importin7 in dental mesenchymal cells

Msx1 is essential for the maintenance of the odontogenic fate of dental mesenchymal cells, and is regulated by BMP/Smad1/5 signaling in a Smad4-independent manner. However, the exact co-factors that assist pSmad1/5 entering the nucleus to regulate Msx1 in dental mesenchymal cells are still unknown....

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Veröffentlicht in:	Cells & development 2022-03, Vol.169, p.203763-203763, Article 203763
Hauptverfasser:	She, Yawei, Zhang, Yue, Xiao, Ziqiu, Yuan, Guohua, Yang, Guobin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BMP4 Bone Morphogenetic Protein 4 - genetics Dental mesenchymal cells importin7 Mesoderm - metabolism Mice Msx1 MSX1 Transcription Factor - genetics Odontogenesis - genetics pSmad1/5 Signal Transduction Smad1 Protein Smad5 Protein Transcription Factors - metabolism
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