Sandwich-type microRNA biosensor based on graphene oxide incorporated 3D-flower-like MoS2 and AuNPs coupling with HRP enzyme signal amplification

A sandwich electrochemical biosensing strategy for ultrasensitive detection of miRNA-21 was developed by using graphene oxide incorporated 3D-flower-like MoS 2 (3D MoS 2 -rGO) nanocomposites as the substrate and horseradish peroxidase (HRP)-functionalized DNA strand 1 (S1)-gold nanoparticles (S1-AuN...

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Veröffentlicht in:	Mikrochimica acta (1966) 2022-01, Vol.189 (1), p.49-49, Article 49
Hauptverfasser:	Dong, Jiangbo, Yang, Huisi, Zhao, Jiaying, Wen, Li, He, Congjuan, Hu, Zhikun, Li, Jiawei, Huo, Danqun, Hou, Changjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Analytical Chemistry Biosensors Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Graphene Hydrogen peroxide Hydroquinone Microengineering MicroRNAs Molybdenum disulfide Nanochemistry Nanocomposites Nanoparticles Nanotechnology Original Paper Peroxidase Ribonucleic acid RNA Sandwich structures Selectivity Silver chloride Substrates Three dimensional flow
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