Confused about Confusion

Confusion developed in a 49-year-old woman with relapsed diffuse large B-cell lymphoma within days after she received CAR-T therapy. She had difficulty putting words together and was disoriented but had no focal abnormalities noted during the neurologic examination.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2022-01, Vol.386 (1), p.80-87
Hauptverfasser:	Spanjaart, Anne M, van der Valk, Fleur M, van Rooijen, Geeske, Brouwer, Matthijs C, Kersten, Marie J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Antiviral Agents - therapeutic use B-cell lymphoma Brain - diagnostic imaging Brain - pathology Case reports Clinical Medicine Clinical Medicine General Confusion Confusion - etiology Cytokines Delirium Diagnosis, Differential Disease prevention Encephalitis Female Fever Hallucinations Hematology Herpesvirus 6, Human - isolation & purification Humans Immunotherapy, Adoptive - adverse effects Infectious Disease Leukemia Limbic Encephalitis - diagnostic imaging Limbic Encephalitis - virology Lymphocytes B Lymphoma Lymphoma, Large B-Cell, Diffuse - therapy Magnetic Resonance Imaging Meningitis Metabolism Middle Aged Neurology Neurosurgery Neurotoxicity Oncology Patients Psychosis Receptors, Chimeric Antigen Roseolovirus Infections - chemically induced Roseolovirus Infections - drug therapy Tomography Treatments in Oncology Viral Infections Viral Load Viruses Vital signs
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Beschreibung
Zusammenfassung:	Confusion developed in a 49-year-old woman with relapsed diffuse large B-cell lymphoma within days after she received CAR-T therapy. She had difficulty putting words together and was disoriented but had no focal abnormalities noted during the neurologic examination.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMcps2114818