Microfluidic Size Exclusion Chromatography (μSEC) for Extracellular Vesicles and Plasma Protein Separation

Extracellular vesicles (EVs) are recognized as next generation diagnostic biomarkers due to their disease‐specific biomolecular cargoes and importance in cell–cell communications. A major bottleneck in EV sample preparation is the inefficient and laborious isolation of nanoscale EVs (≈50–200 nm) fro...

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Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2022-02, Vol.18 (6), p.e2104470-n/a
Hauptverfasser:	Leong, Sheng Yuan, Ong, Hong Boon, Tay, Hui Min, Kong, Fang, Upadya, Megha, Gong, Lingyan, Dao, Ming, Dalan, Rinkoo, Hou, Han Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumins Biological properties Biomarkers blood Blood Proteins - metabolism Chromatography Chromatography, Gel Extracellular vesicles Extracellular Vesicles - metabolism Flow cytometry Fluorescence Fractionation Humans Ions microfluidic Microfluidics miniaturization Modulus of elasticity Nanoparticles Nanotechnology Plasma Proteins Response time Size exclusion chromatography Vesicles
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