New insights into the regulatory roles of glutathione in NLRP3-inflammasome-mediated immune and inflammatory responses

Abstract Glutathione (GSH) is the most abundant non-protein thiol (-SH) in mammalian cells. Its synthesis and metabolism serve to maintain cellular reduction–oxidation (redox) homeostasis, which is important for multiple cellular processes including proliferation, differentiation and death. An accum...

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Veröffentlicht in:Journal of biochemistry (Tokyo) 2022-04, Vol.171 (4), p.367-377
Hauptverfasser: Zhang, Tianli, Tsutsuki, Hiroyasu, Li, Xiaoyan, Sawa, Tomohiro
Format: Artikel
Sprache:eng
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