Effectiveness of prophylactic antiviral therapy in reducing HBV reactivation for HBsAg-positive recipients following allogeneic hematopoietic stem cell transplantation: a multi-institutional experience from an HBV endemic area

Hepatitis B virus reactivation (HBVr) is not uncommon in allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients. Hepatitis B surface antigen (HBsAg)-positive patients receiving allo-HSCT have a very high risk of HBVr. However, the validity of prophylactic antiviral treatment in HB...

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Veröffentlicht in:	Annals of hematology 2022-03, Vol.101 (3), p.631-641
Hauptverfasser:	Wu, Yibo, Chen, Yi, Zhu, Panpan, Ye, Baodong, Lu, Ying, Shi, Jimin, Tan, Yamin, Zhao, Yanmin, Yu, Jian, Lai, Xiaoyu, Lan, Jianping, Si, Ting, Ni, Lihong, Huang, He, Luo, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antigens Antiviral Agents - therapeutic use Antiviral drugs Bone marrow Cytomegalovirus Disease prevention Female Graft versus host disease Guanine - analogs & derivatives Guanine - therapeutic use Hematology Hematopoietic Stem Cell Transplantation - adverse effects Hepatitis B Hepatitis B - blood Hepatitis B - etiology Hepatitis B - prevention & control Hepatitis B - virology Hepatitis B Surface Antigens - blood Hepatitis B virus - drug effects Hepatitis B virus - physiology Hospitals Humans Laboratories Lamivudine - therapeutic use Leukemia Male Medicine Medicine & Public Health Middle Aged Oncology Original Article Retrospective Studies Serology Stem cell transplantation Transplantation, Homologous - adverse effects Virus Activation - drug effects Young Adult
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