The potential use of serum interleukin-21 as biomarker for lupus nephritis activity compared to cytokines of the tumor necrosis factor (TNF) family

Objective Lupus nephritis (LN) is a significant consequence of systemic lupus erythematosus (SLE). To the best of our knowledge, this is the first work that focuses on evaluation of serum interleukin (IL-) 21 as a diagnostic biomarker of LN activity, compared to B lymphocyte stimulator (BlyS), tumor...

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Veröffentlicht in:	Lupus 2022-01, Vol.31 (1), p.55-64
Hauptverfasser:	Shater, Hend, Fawzy, Mary, Farid, Alyaa, El-Amir, Azza, Fouad, Salwa, Madbouly, Neveen
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Biopsy BLyS protein Correlation analysis Cytokines Cytokines - immunology Female Humans Interleukin 21 Interleukins - immunology Lupus Lupus Erythematosus, Systemic - diagnosis Lupus nephritis Lupus Nephritis - diagnosis Lymphocytes B Necrosis Nephritis Proteinuria Serum levels Systemic lupus erythematosus Tumor necrosis factor Tumor Necrosis Factor-alpha - chemistry Tumor Necrosis Factor-alpha - immunology Tumor necrosis factor-TNF
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