Is 5q deletion in de novo Acute Myelogenous Leukemia (AML) with excess blasts a surrogate marker for the cryptic t(7;21)(p22;q22)? A case report and review of literature

•Cryptic or semi-cryptic translocation, t(7;21)(p22;q22) is a rare yet recurring abnormality in acute myeloid leukemia (AML).•Majority of cases with t(7;21)(p22;q22) are associated with a 5q deletion.•We propose that 5q deletion seen in de novo AML may be a surrogate marker for the cryptic t(7;21)(p...

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