Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)

The aim of the present study was to investigate effects of per- and polyfluoroalkyl substances (PFAS), both single compounds and a mixture of these, using precision-cut liver slices (PCLS) from Atlantic cod (Gadus morhua). PCLS were exposed for 48 h to perfluorooctane sulfonate (PFOS), perfluoroocta...

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Veröffentlicht in:	The Science of the total environment 2022-03, Vol.814, p.152732-152732, Article 152732
Hauptverfasser:	Dale, Karina, Yadetie, Fekadu, Horvli, Torill, Zhang, Xiaokang, Frøysa, Håvard Guldbrandsen, Karlsen, Odd André, Goksøyr, Anders
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkanesulfonic Acids - metabolism Alkanesulfonic Acids - toxicity Animals Cholesterol Environmental Pollutants - metabolism Ferroptosis Fish Fluorocarbons - analysis Gadus morhua - genetics Liver - chemistry Mixture toxicity Oxidative Stress Perfluoroalkyl acids (PFAA) PFOS Receptors, Cytoplasmic and Nuclear - metabolism
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