Exogenous artificial DNA forms chromatin structure with active transcription in yeast

Yeast artificial chromosomes (YACs) are important tools for sequencing, gene cloning, and transferring large quantities of genetic information. However, the structure and activity of YAC chromatin, as well as the unintended impacts of introducing foreign DNA sequences on DNA-associated biochemical e...

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Veröffentlicht in:Science China. Life sciences 2022-05, Vol.65 (5), p.851-860
Hauptverfasser: Zhou, Jianting, Zhang, Chao, Wei, Ran, Han, Mingzhe, Wang, Songduo, Yang, Kaiguang, Zhang, Lihua, Chen, Weigang, Wen, Mingzhang, Li, Cheng, Tao, Wei, Yuan, Ying-Jin
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