Hydroxychloroquine blood levels predicts flare in childhood-onset lupus nephritis

Objective Low hydroxychloroquine (HCQ) blood levels are predictors of flare in adult lupus. Childhood-onset systemic lupus erythematosus (cSLE) has high morbidity with renal involvement in up to 80% of cases. The aim of this study is to determine the HCQ cut-off levels which predicts flare in childh...

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Veröffentlicht in:	Lupus 2022-01, Vol.31 (1), p.97-104
Hauptverfasser:	Andrade Balbi, Verena, Artur Silva, Clovis, Nascimento Pedrosa, Tatiana, Maria Rodrigues Pereira, Rosa, Maria de Arruda Campos, Lucia, Pires Leon, Elaine, Duarte, Nilo, Melechco Carvalho, Valdemir, Gofinet Pasoto, Sandra, Cordeiro do Rosário, Debora, Kolachinski Brandao, Leticia, I Brunner, Hermine, Bonfá, Eloisa, Emi Aikawa, Nadia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antirheumatic Agents - therapeutic use Blood levels Children Chromatography, Liquid Humans Hydroxychloroquine Hydroxychloroquine - blood Hydroxychloroquine - therapeutic use Liquid chromatography Lupus Lupus Erythematosus, Systemic - drug therapy Lupus nephritis Lupus Nephritis - diagnosis Lupus Nephritis - drug therapy Mass spectroscopy Morbidity Nephritis Prednisone Systemic lupus erythematosus
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