Single-Cell Digital Microfluidic Mass Spectrometry Platform for Efficient and Multiplex Genotyping of Circulating Tumor Cells

Gene mutation profiling of heterogeneous circulating tumor cells (CTCs) offers comprehensive and real-time molecular information of tumors for targeted therapy guidance, but the lack of efficient and multiplex genotyping techniques for single-CTC analysis greatly hinders its development and clinical...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Analytical chemistry (Washington) 2022-01, Vol.94 (2), p.1108-1117
Hauptverfasser:	Ruan, Qingyu, Yang, Jian, Zou, Fenxiang, Chen, Xiaofeng, Zhang, Qianqian, Zhao, Kaifeng, Lin, Xiaoye, Zeng, Xi, Yu, Xiyuan, Wu, Lingling, Lin, Shuichao, Zhu, Zhi, Yang, Chaoyong
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Cancer Cell Line, Tumor Cell Separation - methods Chemistry Deoxyribonucleic acid DNA Gene sequencing Genomes Genotype Genotypes Genotyping Humans Ionization Ions Mass Spectrometry Mass spectroscopy Microfluidics Microfluidics - methods Multiplexing Mutation Neoplastic Cells, Circulating - pathology Nucleotide sequence Point mutation Sarcoma Scientific imaging Single-Cell Analysis - methods Spectroscopy Tumor cells Tumors Wettability
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!