Ginkgo biloba Extract Inhibited Cell Proliferation and Invasion by Stimulating TET2 Expression Through miR-29a in Colorectal Carcinoma Cells

extract (GBE) has antitumor and antioxidant properties, which play a role in regulating gene and protein expression. The ten-eleven translocation (TET) proteins have the ability to regulate epigenetic modifications. However, the abnormal expression of TET2 protein has also been demonstrated in cance...

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Veröffentlicht in:	DNA and cell biology 2022-02, Vol.41 (2), p.169-178
Hauptverfasser:	Li, Chengshun, Peng, Chuanni, Jiang, Ziping, Hu, Haobo, Lin, Chao, Gao, Yongjian, Liu, Da, Sun, Baozhen, Wang, Dongxu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticancer properties Antioxidants Apoptosis Apoptosis - drug effects Apoptosis - genetics Cancer Cell growth Cell Line, Tumor Cell migration Cell Movement - drug effects Cell Movement - genetics Cell proliferation Cell Proliferation - drug effects Colorectal carcinoma Colorectal Neoplasms - drug therapy Colorectal Neoplasms - genetics Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Dioxygenases - genetics DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Epigenetics Gene expression Gene Expression Regulation, Neoplastic - drug effects Genomes Ginkgo biloba Ginkgo biloba - chemistry Ginkgo Extract Humans Mice Mice, Nude MicroRNAs - genetics MicroRNAs - metabolism miRNA Neoplasm Invasiveness Plant Extracts - pharmacology Protein expression Protein transport Proteins Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Ribonucleic acid RNA Translocation Tumors Xenograft Model Antitumor Assays
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