SF3B14 is involved in the centrosome regulation through splicing of TUBGCP6 pre-mRNA

Splicing precursor messenger RNA (pre-mRNA) is a critical step to produce physiologically functional protein. Splicing failure not only gives rise to dysfunctional proteins but also generates abnormal protein function, which causes several diseases. Several pre-mRNA splicing factors are reported to...

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Veröffentlicht in:	Biochemical and biophysical research communications 2022-01, Vol.588, p.133-139
Hauptverfasser:	Kato, Kazashi, Udagawa, Rina, Hayashi, Yuki, Maki, Masayoshi, Yanagida, Makiko, Higashiura, Sae, Yagishita, Reina, Shimamoto, Haruka, Kimura, Keiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Centrosome - metabolism Centrosomes Chromosomes, Human - metabolism HeLa Cells Humans Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - metabolism Mitosis Phosphoproteins - metabolism RNA Precursors - genetics RNA Precursors - metabolism RNA Splicing - genetics RNA Splicing Factors - metabolism Splicing factors TUBGCP6
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