Impact of cancer metabolism on therapy resistance – Clinical implications

Despite an increasing arsenal of anticancer therapies, many patients continue to have poor outcomes due to the therapeutic failures and tumor relapses. Indeed, the clinical efficacy of anticancer therapies is markedly limited by intrinsic and/or acquired resistance mechanisms that can occur in any t...

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Veröffentlicht in:	Drug resistance updates 2021-12, Vol.59, p.100797-100797, Article 100797
Hauptverfasser:	Gonçalves, Ana Cristina, Richiardone, Elena, Jorge, Joana, Polónia, Bárbara, Xavier, Cristina P.R., Salaroglio, Iris Chiara, Riganti, Chiara, Vasconcelos, M. Helena, Corbet, Cyril, Sarmento-Ribeiro, Ana Bela
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Cancer metabolism Glycolysis Humans Immunotherapy - methods Intratumor heterogeneity Metabolic plasticity Neoplasms - drug therapy Neoplasms - genetics Oxidative phosphorylation Precision Medicine Therapy resistance Tumor Microenvironment
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