Transcriptomics and machine learning to advance schizophrenia genetics: A case-control study using post-mortem brain data

Alterations of the expression of a variety of genes have been reported in patients with schizophrenia (SCZ). Moreover, machine learning (ML) analysis of gene expression microarray data has shown promising preliminary results in the study of SCZ. Our objective was to evaluate the performance of ML in...

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Veröffentlicht in:	Computer methods and programs in biomedicine 2022-02, Vol.214, p.106590-106590, Article 106590
Hauptverfasser:	Qi, Bill, Boscenco, Sonia, Ramamurthy, Janani, Trakadis, Yannis J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics Brain Case-Control Studies Dorsolateral Prefrontal Cortex Humans Machine Learning Post-mortem Schizophrenia Schizophrenia - genetics Transcriptome Transcriptomics
Online-Zugang:	Volltext
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