Bimatoprost-Loaded Silica Shell-Coated Nanoparticles-Laden Soft Contact Lenses to Manage Glaucoma: In Vitro and In Vivo Studies

Currently, glaucoma is managed by frequent instillation of bimatoprost eye drop therapy, which showed very poor ocular bioavailability. Contact lens is widely used as medical device to improve the drug retention on the ocular tissues. However, the traditional methods of drug loading in the contact l...

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Veröffentlicht in:	AAPS PharmSciTech 2021-12, Vol.23 (1), p.33-33
Hauptverfasser:	Xiaojie, He, Fagang, Jiang, Jun, Jing, Chunfang, Wang, Chengquan, Li, Xinghua, Wang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bimatoprost Contact Lenses, Hydrophilic Drug Delivery Systems Glaucoma - drug therapy Nanoparticles Rabbits Silicon Dioxide - therapeutic use
Online-Zugang:	Volltext
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