Rapid measurement of T1–T2 relaxation correlation with a Look-Locker sequence

[Display omitted] •A Look-Locker based T1*–T2* pulse sequence was designed.•Designed T1*–T2* pulse sequence has a high collection efficiency and good accuracy.•T1*–T2* correlation provides quantitative information on complex samples. Measurement of longitudinal–transverse (T1–T2*) relaxation may be...

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Veröffentlicht in:Journal of magnetic resonance (1997) 2022-02, Vol.335, p.107123-107123, Article 107123
Hauptverfasser: Guo, Jiangfeng, Zamiri, Mohammad Sadegh, Balcom, Bruce J.
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container_title Journal of magnetic resonance (1997)
container_volume 335
creator Guo, Jiangfeng
Zamiri, Mohammad Sadegh
Balcom, Bruce J.
description [Display omitted] •A Look-Locker based T1*–T2* pulse sequence was designed.•Designed T1*–T2* pulse sequence has a high collection efficiency and good accuracy.•T1*–T2* correlation provides quantitative information on complex samples. Measurement of longitudinal–transverse (T1–T2*) relaxation may be time-consuming for samples with a long T1 lifetime. In this work, a fast measurement method of T1*–T2* relaxation correlation was presented based on a saturation recovery Look-Locker sequence. T1* is the effective T1 lifetime. The T1 lifetime can be calculated from the measured T1* lifetime and acquisition parameters. The new measurement method was verified by numerical simulation. Three representative samples, corn starch, Advil caplets, and shale in the fields of food, pharmaceutics, and energy, were employed as test samples. Comparisons of T1*–T2* and T1–T2* relaxation correlations show that the new two-dimensional magnetic resonance pulse sequence works well, with a high collection efficiency and good accuracy.
doi_str_mv 10.1016/j.jmr.2021.107123
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Measurement of longitudinal–transverse (T1–T2*) relaxation may be time-consuming for samples with a long T1 lifetime. In this work, a fast measurement method of T1*–T2* relaxation correlation was presented based on a saturation recovery Look-Locker sequence. T1* is the effective T1 lifetime. The T1 lifetime can be calculated from the measured T1* lifetime and acquisition parameters. The new measurement method was verified by numerical simulation. Three representative samples, corn starch, Advil caplets, and shale in the fields of food, pharmaceutics, and energy, were employed as test samples. 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subjects Advil caplets
Corn starch
Look-Locker sequence
Magnetic resonance
Shale
T1–T2 relaxation correlation
title Rapid measurement of T1–T2 relaxation correlation with a Look-Locker sequence
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