Differential translational regulation of host exosomal proteins play key role in immunomodulation in antimony resistance in Visceral Leishmaniasis: A proteomic profiling study

In host-pathogen interactions, exosomal secretions are crucial for cell to cell communication and have an established role in immunomodulation. Protozoans, including Leishmania, modulates their host vesicular secretions for better survival; although the role of exosomal secretions in unresponsive ag...

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Veröffentlicht in:	Acta tropica 2022-02, Vol.226, p.106268-106268, Article 106268
Hauptverfasser:	Abhishek, Kumar, Kumar, Ajay, Sardar, Abul Hasan, Vijayakumar, Saravanan, Dikhit, Manas Ranjan, Kumar, Ashish, Kumar, Vinod, Das, Sushmita, Das, Pradeep
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimony - therapeutic use Antimony resistance Antimony Sodium Gluconate - therapeutic use Antiprotozoal Agents - pharmacology Drug Resistance Exosomes Humans Immune modulatory proteins Immunomodulation LC-MS/MS Leishmania donovani Leishmaniasis, Visceral - drug therapy Proteomics Raw macrophages
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