Discovery of a novel class of small-molecule antibacterial agents against Staphylococcus aureus

With constantly increasing resistance against the known antibiotics, the search for novel antibacterial compounds is a challenge. The number of synthetic antibacterial agents is limited. We discovered novel small-molecule antibacterial agents that are accessible a simple two-step procedure. The eval...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Future medicinal chemistry 2022-03, Vol.14 (5), p.299-305
Hauptverfasser:	Kreutzer, David, Gehrmann, Robin, Kincses, Annámaria, Szemerédi, Nikoletta, Spengler, Gabriella, Molnár, Josef, Hilgeroth, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Acridines - chemistry Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Cell Line Cell Survival - drug effects Humans Microbial Sensitivity Tests Small Molecule Libraries - chemistry Small Molecule Libraries - pharmacology Staphylococcus aureus - drug effects Structure-Activity Relationship
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!