Surfactin-oleogel with therapeutic potential for inflammatory acne vulgaris induced by Propionibacterium acnes

Accumulating evidence suggested that suppression of Propionibacterium acnes- induced inflammation was a promising strategy to alleviate acne vulgaris. This study evaluated the alleviating effect of surfactin-oleogel on P. acnes -induced inflammatory acne vulgaris in mice. Epidermis morphology and hi...

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Veröffentlicht in:	Applied microbiology and biotechnology 2022, Vol.106 (2), p.549-562
Hauptverfasser:	Shan, Mengyuan, Meng, Fanqiang, Tang, Chao, Zhou, Libang, Lu, Zhaoxin, Lu, Yingjian
Format:	Artikel
Sprache:	eng
Schlagworte:	Acne Acne Vulgaris - drug therapy Animals Anti-Inflammatory Agents - therapeutic use Antiacne agents Biomedical and Life Sciences Biotechnological Products and Process Engineering Biotechnology Catalase Cholesterol Colonies Cyclooxygenase-2 Cytokines Epidermis Erythema Fatty acids Glutathione Glutathione peroxidase IL-1β Inflammation Interleukins Life Sciences Linoleic acid Mice Microbial Genetics and Genomics Microbiology NF-kappa B NF-κB protein Nitric oxide Nitric-oxide synthase Organic Chemicals Oxidative stress Peroxidase Propionibacterium acnes Signal transduction Superoxide dismutase Surface active agents Surfactin Testing TLR2 protein Toll-like receptors Triglycerides Tumor necrosis factor-α Tumors
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