Clinicopathological significance of DAPK gene promoter hypermethylation in non-small cell lung cancer: A meta-analysis

Background Death-associated protein kinase (DAPK) has a strong function of tumor suppression involving apoptosis regulation, autophagy, and metastasis inhibition. Hypermethylation of CpG islands in DAPK gene promoter region is one of the important ways to inactivate this tumor suppressor gene, which...

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Veröffentlicht in:	The International journal of biological markers 2022-03, Vol.37 (1), p.47-57
Hauptverfasser:	Chen, Zhimao, Fan, Yu, Liu, Xiangzheng, Shang, Xueqian, Qi, Kang, Zhang, Shijie
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Autophagy Carcinogenesis Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - pathology CpG islands Death-associated protein kinase Death-Associated Protein Kinases - genetics DNA methylation DNA Methylation - genetics Humans Kinases Lung cancer Lung Neoplasms - genetics Lung Neoplasms - pathology Medical prognosis Meta-analysis Metastases Non-small cell lung carcinoma Promoter Regions, Genetic Small cell lung carcinoma Squamous cell carcinoma Tumor markers Tumor suppressor genes Tumors
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