The Antagonism of Corticotropin-Releasing Factor Receptor-1 in Brain Suppress Stress-Induced Propofol Self-Administration in Rats

Propofol addiction has been detected in humans and rats, which may be facilitated by stress. Corticotropin-releasing factor acts through the corticotropin-releasing factor (CRF) receptor-1 (CRF1R) and CRF2 receptor-2 (CRF2R) and is a crucial candidate target for the interaction between stress and dr...

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Veröffentlicht in:	Frontiers in behavioral neuroscience 2021-12, Vol.15, p.775209-775209, Article 775209
Hauptverfasser:	Dong, Zhanglei, Zhang, Gaolong, Xiang, Saiqiong, Jiang, Chenchen, Chen, Zhichuan, Li, Yan, Huang, Bingwu, Zhou, Wenhua, Lian, Qingquan, Wu, Binbin
Format:	Artikel
Sprache:	eng
Schlagworte:	addiction Addictions Addictive behaviors Anesthesia Antalarmin Behavior Behavioral Sciences Catheters Cocaine Corticotropin-releasing hormone CRF D1 receptor Dopamine Dopamine D1 receptors Drug abuse Drug self-administration Glucocorticoids Laboratory animals Life Sciences & Biomedicine Neuroscience Neurosciences Neurosciences & Neurology Nucleus accumbens Propofol Reinforcement Science & Technology stress Sucrose Ventricle Ventricles (cerebral)
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