Statins downregulate YAP and TAZ and exert anti‐cancer effects in canine mammary tumour cells

Canine mammary tumours (CMTs) are the most common neoplasms in intact bitches, and few chemotherapeutic options are available for highly invasive and metastatic tumours. Recent studies have shown the potential involvement of dysregulated Hippo signalling in CMT development and progression. Statins c...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Veterinary & comparative oncology 2022-06, Vol.20 (2), p.437-448
Hauptverfasser:	Vigneau, Anne‐Laurence, Rico, Charlène, Boerboom, Derek, Paquet, Marilène
Format:	Artikel
Sprache:	eng
Schlagworte:	dogs hippo pathway hydroxymethylglutaryl‐CoA reductase inhibitors mammary neoplasms YAP and TAZ
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!