IMPROvE-CED Trial: Intracoronary Autologous CD34+ Cell Therapy for Treatment of Coronary Endothelial Dysfunction in Patients With Angina and Nonobstructive Coronary Arteries

Coronary endothelial dysfunction (CED) causes angina/ischemia in patients with nonobstructive coronary artery disease (NOCAD). Patients with CED have decreased number and function of CD34+ cells involved in normal vascular repair with microcirculatory regenerative potential and paracrine anti-inflam...

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Veröffentlicht in:	Circulation research 2022-02, Vol.130 (3), p.326-338
Hauptverfasser:	Corban, Michel T., Toya, Takumi, Albers, Diana, Sebaali, Faten, Lewis, Bradley R., Bois, John, Gulati, Rajiv, Prasad, Abhiram, Best, Patricia J.M., Bell, Malcolm R., Rihal, Charanjit S., Prasad, Megha, Ahmad, Ali, Lerman, Lilach O., Solseth, Mary L., Winters, Jeffrey L., Dietz, Allan B., Lerman, Amir
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Angina Pectoris - etiology Angina Pectoris - therapy Antigens, CD34 - genetics Antigens, CD34 - metabolism Coronary Artery Disease - complications Coronary Artery Disease - therapy Endothelium, Vascular - pathology Female Humans Leukapheresis - methods Male Middle Aged T-Lymphocytes - metabolism T-Lymphocytes - transplantation Transplantation, Autologous
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