Genetic Predisposition to Diabetes and Abdominal Aortic Aneurysm: A Two Stage Mendelian Randomisation Study

Observational studies demonstrate an inverse association between type II diabetes and abdominal aortic aneurysm (AAA) for reasons that are unclear. The aim of this study was to clarify the causal association between type II diabetes predisposition and AAA using Mendelian randomisation. Effect estima...

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Veröffentlicht in:	European journal of vascular and endovascular surgery 2022-03, Vol.63 (3), p.512-519
Hauptverfasser:	Morris, Dylan R., Jones, Gregory T., Holmes, Michael V., Bown, Matthew J., Bulbulia, Richard, Singh, Tejas P., Golledge, Jonathan
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal aortic aneurysm Aortic Aneurysm, Abdominal - epidemiology Aortic Aneurysm, Abdominal - genetics Diabetes Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Genetic Predisposition to Disease Genome-Wide Association Study Humans Mendelian randomisation Mendelian Randomization Analysis - methods Polymorphism, Single Nucleotide
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