Current topics in Epidermolysis bullosa: Pathophysiology and therapeutic challenges

Epidermolysis bullosa (EB) is a group of inherited skin and mucosal fragility disorders resulting from mutations in genes encoding basement membrane zone (BMZ) components or proteins that maintain the integrity of BMZ and adjacent keratinocytes. More than 30 years have passed since the first causati...

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Veröffentlicht in:	Journal of dermatological science 2021-12, Vol.104 (3), p.164-176
Hauptverfasser:	Natsuga, Ken, Shinkuma, Satoru, Hsu, Chao-Kai, Fujita, Yasuyuki, Ishiko, Akira, Tamai, Katsuto, McGrath, John A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blister Cell therapy Epidermolysis bullosa Epidermolysis Bullosa - genetics Epidermolysis Bullosa - therapy Gene therapy Humans Keratinocytes Mutation Skin Stem cell Wound healing
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