Metal-Free Annulation of 2‑Nitrobenzyl Alcohols and Tetrahydroisoquinolines toward the Divergent Synthesis of Quinazolinones and Quinazolinethiones

A simple metal-free method for the synthesis of quinazolinones from commercially available 2-nitrobenzyl alcohols and tetrahydroisoquinolines is developed. The reaction conditions were tolerant of an array of functionalities such as halogen, tertiary amine, protected alcohol, and ester groups. Under...

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Veröffentlicht in:	Journal of organic chemistry 2022-01, Vol.87 (1), p.103-113
Hauptverfasser:	Ly, Duc, Nguyen, Thao T, Tran, Cam T. H, Nguyen, Vy P. T, Nguyen, Khang X, Pham, Phuc H, Le, Nhan T. H, Nguyen, Tung T, Phan, Nam T. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Metals Quinazolinones Tetrahydroisoquinolines
Online-Zugang:	Volltext
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