Tris(1,3-dichloro-2-propyl) phosphate reduces longevity through a specific microRNA-mediated DAF-16/FoxO in an unconventional insulin/insulin-like growth factor‑1 signaling pathway

Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) has received concerns due to its frequent detection in environmental media and biological samples. Our previous study has indicated TDCPP reduced the lifespan of Caenorhabditis elegans (C. elegans) by triggering an unconventional insulin/insulin-like gro...

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Veröffentlicht in:	Journal of hazardous materials 2022-03, Vol.425, p.128043-128043, Article 128043
Hauptverfasser:	Wang, Chen, Li, Yeyong, Zeng, Lingjun, Shi, Chongli, Peng, Yi, Li, Hui, Chen, Haibo, Yu, Jun, Zhang, Jin, Cheng, Biao, Pan, Ruolin, Wang, Xiaoli, Xiang, Minghui, Huang, Yuan, Liu, Yongdi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans - genetics Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - genetics Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism Insulin Insulin-Like Growth Factor I Longevity MicroRNAs - genetics MiR-48 MiR-84 MiRNAs Phosphates Signal Transduction Tris(1,3-dichloro-2-propyl) phosphate
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