Tadalafil in Increasing Doses: The Influence on Coronary Blood Flow and Oxidative Stress in Isolated Rat Hearts

Abstract Introduction: This study aimed to assess the influence of different doses of tadalafil on coronary flow and oxidative stress in isolated rat hearts. Methods: The hearts of male Wistar albino rats (n = 48) were retrogradely perfused according to the Langendorff technique at gradually increas...

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Veröffentlicht in:	Pharmacology 2022-03, Vol.107 (3-4), p.150-159
Hauptverfasser:	Banjac, Nada M., Vasović, Velibor M., Stilinović, Nebojša P., Prodanović, Dušan V., Tomas Petrović, Ana D., Vasović, Lucija V., Jakovljević, Vladimir Lj
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Coronary Circulation - physiology Ethylenediaminetetraacetic acid Male Myocardium - metabolism NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide - metabolism Oxidative Stress Rats Rats, Wistar Research Article Superoxide Tadalafil Tadalafil - metabolism Tadalafil - pharmacology
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