Hesperetin derivative-16 attenuates CCl4-induced inflammation and liver fibrosis by activating AMPK/SIRT3 pathway

Liver fibrosis, a chronic inflammatory healing reaction, progresses to hepatocirrhosis without effective intervention. Hesperetin derivative (HD-16), a monomer compound derived from hesperitin, exerts anti-inflammatory and hepatoprotective effects against a spectrum of liver diseases. However, the a...

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Veröffentlicht in:	European journal of pharmacology 2022-01, Vol.915, p.174530, Article 174530
Hauptverfasser:	Li, Juan-Juan, Jiang, He-Chun, Wang, Ao, Bu, Fang-Tian, Jia, Peng-Cheng, Zhu, Sai, Zhu, Lin, Huang, Cheng, Li, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	AMPK HD-16 Inflammation Liver fibrosis SIRT3
Online-Zugang:	Volltext
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