Polymeric PD-L1 blockade nanoparticles for cancer photothermal-immunotherapy

Checkpoint inhibitors, such as antibodies blocking the PD-1/PD-L1 pathway, are among the most promising immunotherapies to treat metastatic cancers, but their response rate remains low. In addition, the usage of monoclonal antibodies as checkpoint inhibitors is associated with a series of drawbacks....

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Veröffentlicht in:	Biomaterials 2022-01, Vol.280, p.121312-121312, Article 121312
Hauptverfasser:	Yu, Yunjian, Li, Jie, Song, Boyi, Ma, Zhuang, Zhang, Yufei, Sun, Haonan, Wei, Xiaosong, Bai, Yayun, Lu, Xueguang, Zhang, Peng, Zhang, Xinge
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal Antitumor immunity B7-H1 Antigen Cell Line, Tumor Humans Immunotherapy Metastatic cancer Nanoparticles Neoplasms - therapy PD-L1 blockade Photothermal treatment Polymeric nanoparticle
Online-Zugang:	Volltext
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