Rectal cancer: Maximizing local control and minimizing toxicity
Adoption of multimodality treatment approach for rectal cancer has resulted in significant improvements in oncologic outcomes. The roles of chemotherapy, radiation, and surgery in rectal cancer treatment are continuously evolving with the goal of achieving the best possible oncologic and functional...
Gespeichert in:
| Veröffentlicht in: | Journal of surgical oncology 2022-01, Vol.125 (1), p.46-54 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 54 |
|---|---|
| container_issue | 1 |
| container_start_page | 46 |
| container_title | Journal of surgical oncology |
| container_volume | 125 |
| creator | Whelan, Sean Burneikis, Dominykas Kalady, Matthew F. |
| description | Adoption of multimodality treatment approach for rectal cancer has resulted in significant improvements in oncologic outcomes. The roles of chemotherapy, radiation, and surgery in rectal cancer treatment are continuously evolving with the goal of achieving the best possible oncologic and functional outcome while minimizing treatment toxicity. The aim of this review is to summarize the most recent trials focusing on organ‐sparing treatment strategies and the optimal selection of patients for neoadjuvant radiation therapy. |
| doi_str_mv | 10.1002/jso.26743 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2609457212</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2609457212</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3533-bc4c1275964523b57dca745c0571578916046227ec2a45ebe912634090364fa33</originalsourceid><addsrcrecordid>eNp10EtLw0AUBeBBFFurC_-ABNzoIu2dd8eNSPFJpeBjHSbTqUxJMjWTYOuvN21aF4KrWZyPc4eD0CmGPgYgg3nwfSIko3uoi0GJWIEa7qNuk5GYSQUddBTCHACUEuwQdSgbKikx7qLrF2sqnUVGF8aWV9GzXrrcfbviI8q8WQe-qEqfRbqYRrkrdmHll864anWMDmY6C_Zk-_bQ-93t2-ghHk_uH0c349hQTmmcGmYwkbw5zwlNuZwaLRk3wCXmcqiwACYIkdYQzbhNrcJEUAYKqGAzTWkPXbS9i9J_1jZUSe6CsVmmC-vrkBABinFJMGno-R8693VZNL_bKMKAY2jUZatM6UMo7SxZlC7X5SrBkKxXTZpVk82qjT3bNtZpbqe_cjdjAwYt-HKZXf3flDy9TtrKHy-NfjY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2609240510</pqid></control><display><type>article</type><title>Rectal cancer: Maximizing local control and minimizing toxicity</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Whelan, Sean ; Burneikis, Dominykas ; Kalady, Matthew F.</creator><creatorcontrib>Whelan, Sean ; Burneikis, Dominykas ; Kalady, Matthew F.</creatorcontrib><description>Adoption of multimodality treatment approach for rectal cancer has resulted in significant improvements in oncologic outcomes. The roles of chemotherapy, radiation, and surgery in rectal cancer treatment are continuously evolving with the goal of achieving the best possible oncologic and functional outcome while minimizing treatment toxicity. The aim of this review is to summarize the most recent trials focusing on organ‐sparing treatment strategies and the optimal selection of patients for neoadjuvant radiation therapy.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.26743</identifier><identifier>PMID: 34897711</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Cancer therapies ; Chemotherapy, Adjuvant ; Clinical Trials, Phase II as Topic ; Clinical Trials, Phase III as Topic ; Colorectal cancer ; Cytoreduction Surgical Procedures - methods ; Humans ; local excision ; Neoadjuvant Therapy ; Neoplasm Staging ; organ preservation ; Organ Sparing Treatments - methods ; Radiation ; Radiotherapy, Adjuvant ; Randomized Controlled Trials as Topic ; rectal cancer ; Rectal Neoplasms - pathology ; Rectal Neoplasms - therapy ; watch and wait</subject><ispartof>Journal of surgical oncology, 2022-01, Vol.125 (1), p.46-54</ispartof><rights>2021 Wiley Periodicals LLC</rights><rights>2021 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3533-bc4c1275964523b57dca745c0571578916046227ec2a45ebe912634090364fa33</citedby><cites>FETCH-LOGICAL-c3533-bc4c1275964523b57dca745c0571578916046227ec2a45ebe912634090364fa33</cites><orcidid>0000-0002-2114-114X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.26743$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.26743$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34897711$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Whelan, Sean</creatorcontrib><creatorcontrib>Burneikis, Dominykas</creatorcontrib><creatorcontrib>Kalady, Matthew F.</creatorcontrib><title>Rectal cancer: Maximizing local control and minimizing toxicity</title><title>Journal of surgical oncology</title><addtitle>J Surg Oncol</addtitle><description>Adoption of multimodality treatment approach for rectal cancer has resulted in significant improvements in oncologic outcomes. The roles of chemotherapy, radiation, and surgery in rectal cancer treatment are continuously evolving with the goal of achieving the best possible oncologic and functional outcome while minimizing treatment toxicity. The aim of this review is to summarize the most recent trials focusing on organ‐sparing treatment strategies and the optimal selection of patients for neoadjuvant radiation therapy.</description><subject>Cancer therapies</subject><subject>Chemotherapy, Adjuvant</subject><subject>Clinical Trials, Phase II as Topic</subject><subject>Clinical Trials, Phase III as Topic</subject><subject>Colorectal cancer</subject><subject>Cytoreduction Surgical Procedures - methods</subject><subject>Humans</subject><subject>local excision</subject><subject>Neoadjuvant Therapy</subject><subject>Neoplasm Staging</subject><subject>organ preservation</subject><subject>Organ Sparing Treatments - methods</subject><subject>Radiation</subject><subject>Radiotherapy, Adjuvant</subject><subject>Randomized Controlled Trials as Topic</subject><subject>rectal cancer</subject><subject>Rectal Neoplasms - pathology</subject><subject>Rectal Neoplasms - therapy</subject><subject>watch and wait</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10EtLw0AUBeBBFFurC_-ABNzoIu2dd8eNSPFJpeBjHSbTqUxJMjWTYOuvN21aF4KrWZyPc4eD0CmGPgYgg3nwfSIko3uoi0GJWIEa7qNuk5GYSQUddBTCHACUEuwQdSgbKikx7qLrF2sqnUVGF8aWV9GzXrrcfbviI8q8WQe-qEqfRbqYRrkrdmHll864anWMDmY6C_Zk-_bQ-93t2-ghHk_uH0c349hQTmmcGmYwkbw5zwlNuZwaLRk3wCXmcqiwACYIkdYQzbhNrcJEUAYKqGAzTWkPXbS9i9J_1jZUSe6CsVmmC-vrkBABinFJMGno-R8693VZNL_bKMKAY2jUZatM6UMo7SxZlC7X5SrBkKxXTZpVk82qjT3bNtZpbqe_cjdjAwYt-HKZXf3flDy9TtrKHy-NfjY</recordid><startdate>202201</startdate><enddate>202201</enddate><creator>Whelan, Sean</creator><creator>Burneikis, Dominykas</creator><creator>Kalady, Matthew F.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2114-114X</orcidid></search><sort><creationdate>202201</creationdate><title>Rectal cancer: Maximizing local control and minimizing toxicity</title><author>Whelan, Sean ; Burneikis, Dominykas ; Kalady, Matthew F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3533-bc4c1275964523b57dca745c0571578916046227ec2a45ebe912634090364fa33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Cancer therapies</topic><topic>Chemotherapy, Adjuvant</topic><topic>Clinical Trials, Phase II as Topic</topic><topic>Clinical Trials, Phase III as Topic</topic><topic>Colorectal cancer</topic><topic>Cytoreduction Surgical Procedures - methods</topic><topic>Humans</topic><topic>local excision</topic><topic>Neoadjuvant Therapy</topic><topic>Neoplasm Staging</topic><topic>organ preservation</topic><topic>Organ Sparing Treatments - methods</topic><topic>Radiation</topic><topic>Radiotherapy, Adjuvant</topic><topic>Randomized Controlled Trials as Topic</topic><topic>rectal cancer</topic><topic>Rectal Neoplasms - pathology</topic><topic>Rectal Neoplasms - therapy</topic><topic>watch and wait</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Whelan, Sean</creatorcontrib><creatorcontrib>Burneikis, Dominykas</creatorcontrib><creatorcontrib>Kalady, Matthew F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Whelan, Sean</au><au>Burneikis, Dominykas</au><au>Kalady, Matthew F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rectal cancer: Maximizing local control and minimizing toxicity</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J Surg Oncol</addtitle><date>2022-01</date><risdate>2022</risdate><volume>125</volume><issue>1</issue><spage>46</spage><epage>54</epage><pages>46-54</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><abstract>Adoption of multimodality treatment approach for rectal cancer has resulted in significant improvements in oncologic outcomes. The roles of chemotherapy, radiation, and surgery in rectal cancer treatment are continuously evolving with the goal of achieving the best possible oncologic and functional outcome while minimizing treatment toxicity. The aim of this review is to summarize the most recent trials focusing on organ‐sparing treatment strategies and the optimal selection of patients for neoadjuvant radiation therapy.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>34897711</pmid><doi>10.1002/jso.26743</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-2114-114X</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-4790 |
| ispartof | Journal of surgical oncology, 2022-01, Vol.125 (1), p.46-54 |
| issn | 0022-4790 1096-9098 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2609457212 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Cancer therapies Chemotherapy, Adjuvant Clinical Trials, Phase II as Topic Clinical Trials, Phase III as Topic Colorectal cancer Cytoreduction Surgical Procedures - methods Humans local excision Neoadjuvant Therapy Neoplasm Staging organ preservation Organ Sparing Treatments - methods Radiation Radiotherapy, Adjuvant Randomized Controlled Trials as Topic rectal cancer Rectal Neoplasms - pathology Rectal Neoplasms - therapy watch and wait |
| title | Rectal cancer: Maximizing local control and minimizing toxicity |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T17%3A51%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Rectal%20cancer:%20Maximizing%20local%20control%20and%20minimizing%20toxicity&rft.jtitle=Journal%20of%20surgical%20oncology&rft.au=Whelan,%20Sean&rft.date=2022-01&rft.volume=125&rft.issue=1&rft.spage=46&rft.epage=54&rft.pages=46-54&rft.issn=0022-4790&rft.eissn=1096-9098&rft_id=info:doi/10.1002/jso.26743&rft_dat=%3Cproquest_cross%3E2609457212%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2609240510&rft_id=info:pmid/34897711&rfr_iscdi=true |