Janus kinase inhibition in induction treatment of anti‐MDA5 juvenile dermatomyositis‐associated rapidly progressive interstitial lung disease
Tofacitinib has an important role in pediatric rapidly progressive interstitial lung disease (ILD) associated with juvenile dermatomyositis (JDM), an otherwise potentially fatal condition. It may be useful in induction of remission and can be used safely to maintain remission. Serum ferritin and int...
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| Veröffentlicht in: | International journal of rheumatic diseases 2022-02, Vol.25 (2), p.228-231 |
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| container_title | International journal of rheumatic diseases |
| container_volume | 25 |
| creator | Chan Ng, Poh Lin Pauline Mopur, Archana Goh, Daniel Yam Thiam Ramamurthy, Mahesh Babu Lim, Michael Teik Chung Lim, Lee Kean Ooi, Pei Ling Ang, Elizabeth Youning |
| description | Tofacitinib has an important role in pediatric rapidly progressive interstitial lung disease (ILD) associated with juvenile dermatomyositis (JDM), an otherwise potentially fatal condition. It may be useful in induction of remission and can be used safely to maintain remission. Serum ferritin and interleukin‐18 are useful markers for tracking activity and response of JDM‐associated ILD. |
| doi_str_mv | 10.1111/1756-185X.14258 |
| format | Article |
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It may be useful in induction of remission and can be used safely to maintain remission. Serum ferritin and interleukin‐18 are useful markers for tracking activity and response of JDM‐associated ILD.</description><identifier>ISSN: 1756-1841</identifier><identifier>EISSN: 1756-185X</identifier><identifier>DOI: 10.1111/1756-185X.14258</identifier><identifier>PMID: 34882988</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject><![CDATA[Child ; clinical aspects <myositis and related syndromes ; Dermatomyositis ; Dermatomyositis - complications ; Dermatomyositis - drug therapy ; drug treatment <myositis and related syndromes ; drug treatment <pediatric rheumatology ; Ferritin ; Humans ; Inflammatory diseases ; Janus kinase ; Janus Kinase Inhibitors - administration & dosage ; Lung diseases ; Lung Diseases, Interstitial - diagnostic imaging ; Lung Diseases, Interstitial - drug therapy ; Lung Diseases, Interstitial - etiology ; Lung Diseases, Interstitial - pathology ; Male ; Musculoskeletal diseases ; Pediatrics ; Piperidines - administration & dosage ; Pyrimidines - administration & dosage ; Remission ; Remission (Medicine) ; Remission Induction - methods]]></subject><ispartof>International journal of rheumatic diseases, 2022-02, Vol.25 (2), p.228-231</ispartof><rights>2021 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.</rights><rights>International Journal of Rheumatic Diseases © 2022 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3718-48f3a4bbe62180a6ca36c3449211a505ae3354aaad63b597ce2564b10e2157863</citedby><cites>FETCH-LOGICAL-c3718-48f3a4bbe62180a6ca36c3449211a505ae3354aaad63b597ce2564b10e2157863</cites><orcidid>0000-0003-3161-848X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2F1756-185X.14258$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2F1756-185X.14258$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34882988$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chan Ng, Poh Lin Pauline</creatorcontrib><creatorcontrib>Mopur, Archana</creatorcontrib><creatorcontrib>Goh, Daniel Yam Thiam</creatorcontrib><creatorcontrib>Ramamurthy, Mahesh Babu</creatorcontrib><creatorcontrib>Lim, Michael Teik Chung</creatorcontrib><creatorcontrib>Lim, Lee Kean</creatorcontrib><creatorcontrib>Ooi, Pei Ling</creatorcontrib><creatorcontrib>Ang, Elizabeth Youning</creatorcontrib><title>Janus kinase inhibition in induction treatment of anti‐MDA5 juvenile dermatomyositis‐associated rapidly progressive interstitial lung disease</title><title>International journal of rheumatic diseases</title><addtitle>Int J Rheum Dis</addtitle><description>Tofacitinib has an important role in pediatric rapidly progressive interstitial lung disease (ILD) associated with juvenile dermatomyositis (JDM), an otherwise potentially fatal condition. It may be useful in induction of remission and can be used safely to maintain remission. Serum ferritin and interleukin‐18 are useful markers for tracking activity and response of JDM‐associated ILD.</description><subject>Child</subject><subject>clinical aspects <myositis and related syndromes</subject><subject>Dermatomyositis</subject><subject>Dermatomyositis - complications</subject><subject>Dermatomyositis - drug therapy</subject><subject>drug treatment <myositis and related syndromes</subject><subject>drug treatment <pediatric rheumatology</subject><subject>Ferritin</subject><subject>Humans</subject><subject>Inflammatory diseases</subject><subject>Janus kinase</subject><subject>Janus Kinase Inhibitors - administration & dosage</subject><subject>Lung diseases</subject><subject>Lung Diseases, Interstitial - diagnostic imaging</subject><subject>Lung Diseases, Interstitial - drug therapy</subject><subject>Lung Diseases, Interstitial - etiology</subject><subject>Lung Diseases, Interstitial - pathology</subject><subject>Male</subject><subject>Musculoskeletal diseases</subject><subject>Pediatrics</subject><subject>Piperidines - administration & dosage</subject><subject>Pyrimidines - administration & dosage</subject><subject>Remission</subject><subject>Remission (Medicine)</subject><subject>Remission Induction - methods</subject><issn>1756-1841</issn><issn>1756-185X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1uEzEUhS0EoqWwZocssWGTdvw7zjIqf0WpYAESO-vOzE1xmPEEX09RdjwCvCJPUqcpWXSDZcnX9nePj3wYey6qU1HGmaiNnQlnvp4KLY17wI4PJw8PtRZH7AnRuqqsULZ-zI6Udk7OnTtmfz5AnIh_DxEIeYjfQhNyGGMpy-ym9naTE0IeMGY-rjjEHP7--n35emH4errGGHrkHaYB8jhsRyr9VO6BaGwDZOx4gk3o-i3fpPEqIVG43j2VMVEuMPS8n-IV7wJhMfGUPVpBT_jsbj1hX96--Xz-frb8-O7ifLGctaoWbqbdSoFuGrRSuApsC8q2Suu5FAJMZQCVMhoAOqsaM69blMbqRlQohamdVSfs1V63uPoxIWU_BGqx7yHiOJGXtnJGmblTBX15D12PU4rFXaGkFtJaJwt1tqfaNBIlXPlNCgOkrReV36Xld3n4XTb-Nq3S8eJOd2oG7A78v3gKYPbAz_LH2__p-cWn5V74BhPQo7Y</recordid><startdate>202202</startdate><enddate>202202</enddate><creator>Chan Ng, Poh Lin Pauline</creator><creator>Mopur, Archana</creator><creator>Goh, Daniel Yam Thiam</creator><creator>Ramamurthy, Mahesh Babu</creator><creator>Lim, Michael Teik Chung</creator><creator>Lim, Lee Kean</creator><creator>Ooi, Pei Ling</creator><creator>Ang, Elizabeth Youning</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-3161-848X</orcidid></search><sort><creationdate>202202</creationdate><title>Janus kinase inhibition in induction treatment of anti‐MDA5 juvenile dermatomyositis‐associated rapidly progressive interstitial lung disease</title><author>Chan Ng, Poh Lin Pauline ; Mopur, Archana ; Goh, Daniel Yam Thiam ; Ramamurthy, Mahesh Babu ; Lim, Michael Teik Chung ; Lim, Lee Kean ; Ooi, Pei Ling ; Ang, Elizabeth Youning</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3718-48f3a4bbe62180a6ca36c3449211a505ae3354aaad63b597ce2564b10e2157863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Child</topic><topic>clinical aspects <myositis and related syndromes</topic><topic>Dermatomyositis</topic><topic>Dermatomyositis - complications</topic><topic>Dermatomyositis - drug therapy</topic><topic>drug treatment <myositis and related syndromes</topic><topic>drug treatment <pediatric rheumatology</topic><topic>Ferritin</topic><topic>Humans</topic><topic>Inflammatory diseases</topic><topic>Janus kinase</topic><topic>Janus Kinase Inhibitors - administration & dosage</topic><topic>Lung diseases</topic><topic>Lung Diseases, Interstitial - diagnostic imaging</topic><topic>Lung Diseases, Interstitial - drug therapy</topic><topic>Lung Diseases, Interstitial - etiology</topic><topic>Lung Diseases, Interstitial - pathology</topic><topic>Male</topic><topic>Musculoskeletal diseases</topic><topic>Pediatrics</topic><topic>Piperidines - administration & dosage</topic><topic>Pyrimidines - administration & dosage</topic><topic>Remission</topic><topic>Remission (Medicine)</topic><topic>Remission Induction - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chan Ng, Poh Lin Pauline</creatorcontrib><creatorcontrib>Mopur, Archana</creatorcontrib><creatorcontrib>Goh, Daniel Yam Thiam</creatorcontrib><creatorcontrib>Ramamurthy, Mahesh Babu</creatorcontrib><creatorcontrib>Lim, Michael Teik Chung</creatorcontrib><creatorcontrib>Lim, Lee Kean</creatorcontrib><creatorcontrib>Ooi, Pei Ling</creatorcontrib><creatorcontrib>Ang, Elizabeth Youning</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of rheumatic diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chan Ng, Poh Lin Pauline</au><au>Mopur, Archana</au><au>Goh, Daniel Yam Thiam</au><au>Ramamurthy, Mahesh Babu</au><au>Lim, Michael Teik Chung</au><au>Lim, Lee Kean</au><au>Ooi, Pei Ling</au><au>Ang, Elizabeth Youning</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Janus kinase inhibition in induction treatment of anti‐MDA5 juvenile dermatomyositis‐associated rapidly progressive interstitial lung disease</atitle><jtitle>International journal of rheumatic diseases</jtitle><addtitle>Int J Rheum Dis</addtitle><date>2022-02</date><risdate>2022</risdate><volume>25</volume><issue>2</issue><spage>228</spage><epage>231</epage><pages>228-231</pages><issn>1756-1841</issn><eissn>1756-185X</eissn><abstract>Tofacitinib has an important role in pediatric rapidly progressive interstitial lung disease (ILD) associated with juvenile dermatomyositis (JDM), an otherwise potentially fatal condition. It may be useful in induction of remission and can be used safely to maintain remission. Serum ferritin and interleukin‐18 are useful markers for tracking activity and response of JDM‐associated ILD.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>34882988</pmid><doi>10.1111/1756-185X.14258</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0003-3161-848X</orcidid></addata></record> |
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| subjects | Child clinical aspects <myositis and related syndromes Dermatomyositis Dermatomyositis - complications Dermatomyositis - drug therapy drug treatment <myositis and related syndromes drug treatment <pediatric rheumatology Ferritin Humans Inflammatory diseases Janus kinase Janus Kinase Inhibitors - administration & dosage Lung diseases Lung Diseases, Interstitial - diagnostic imaging Lung Diseases, Interstitial - drug therapy Lung Diseases, Interstitial - etiology Lung Diseases, Interstitial - pathology Male Musculoskeletal diseases Pediatrics Piperidines - administration & dosage Pyrimidines - administration & dosage Remission Remission (Medicine) Remission Induction - methods |
| title | Janus kinase inhibition in induction treatment of anti‐MDA5 juvenile dermatomyositis‐associated rapidly progressive interstitial lung disease |
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